Drug that blocks the action of proteasomes, cellular complexes that break down proteins.
Synonyms
Examples for "proteasome inhibitor "
Examples for "proteasome inhibitor "
1 The proteasome inhibitor bortezomib is an efficacious apoptotic agent in many tumor cells.
2 Bortezomib is the first proteasome inhibitor drug tested in human patients.
3 However, a significant proportion of patients who receive a proteasome inhibitor - containing regime show cardiotoxicity.
4 Therefore, the proteasome inhibitor MG132 should be further evaluated for combination therapy with TRAIL.
5 The introduction of proteasome inhibitor and immunomodulatory drugs has considerably changed the treatment paradigm of multiple myeloma.
1 That system is a target for anticancer strategies by using proteasome inhibitors .
2 Nevertheless, the mechanisms of apoptosis induced by proteasome inhibitors remain unclear.
3 Both Kyprolis and Velcade are members of a class known as proteasome inhibitors .
4 Overall, these findings suggest proteasome inhibitors as potential latency reversing agents.
5 Overall, we determined the unique and novel mechanism of FOXM1 suppression by proteasome inhibitors .
Grammar, pronunciation and more
Translations for proteasome endopeptidase complex inhibitors