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Meanings of proteasome endopeptidase complex inhibitors in English

Russian
ингибиторы протеасомы
Spanish
inhibidores del proteasoma

Drug that blocks the action of proteasomes, cellular complexes that break down proteins.

        Related terms
        ингибиторы протеасомы
        Synonyms
        Examples for "proteasome inhibitor"
        Examples for "proteasome inhibitor"
        1
        The proteasome inhibitor bortezomib is an efficacious apoptotic agent in many tumor cells.
        Pubmed
        2
        Bortezomib is the first proteasome inhibitor drug tested in human patients.
        Pubmed
        3
        However, a significant proportion of patients who receive a proteasome inhibitor-containing regime show cardiotoxicity.
        Pubmed
        4
        Therefore, the proteasome inhibitor MG132 should be further evaluated for combination therapy with TRAIL.
        Pubmed
        5
        The introduction of proteasome inhibitor and immunomodulatory drugs has considerably changed the treatment paradigm of multiple myeloma.
        Pubmed
        1
        That system is a target for anticancer strategies by using proteasome inhibitors.
        Pubmed
        2
        Nevertheless, the mechanisms of apoptosis induced by proteasome inhibitors remain unclear.
        Pubmed
        3
        Both Kyprolis and Velcade are members of a class known as proteasome inhibitors.
        Reuters
        4
        Overall, these findings suggest proteasome inhibitors as potential latency reversing agents.
        Pubmed
        5
        Overall, we determined the unique and novel mechanism of FOXM1 suppression by proteasome inhibitors.
        Pubmed
        Translations for proteasome endopeptidase complex inhibitors